A global, science-driven biopharmaceutical company is seeking a Senior Medical Director, Clinical Development to provide strategic and hands-on clinical leadership across late-stage rare disease programs. This role will be highly influential in advancing assets through Phase II and Phase III development, shaping clinical strategy, and preparing programs for potential registration.
Reporting into senior R&D leadership, the Senior Medical Director will lead the development and execution of Clinical Development Plans, oversee the design and delivery of Phase II/III clinical trials, and ensure rigorous medical oversight, patient safety, and data integrity. The role partners closely with Regulatory, Safety, Biostatistics, and Clinical Operations, contributing to global regulatory interactions and key submission activities.
Key focus areas include:
- Clinical leadership of Phase II and Phase III studies, including protocol development, execution, and interpretation
- Medical oversight of ongoing trials, safety monitoring, and CRO/vendor management
- Strategic data analysis and translation of results into clear development and regulatory recommendations
- Cross-functional leadership and influence within a matrixed R&D environment
- Scientific engagement through publications, regulatory meetings, and external collaborations
Ideal background:
- MD or MD/PhD with 8+ years of clinical drug development experience
- Strong track record in late-stage (Phase II/III) program leadership
- Experience in rare disease, or adjacent therapeutic areas preferred
- Confident, collaborative leader with strong scientific judgment and communication skills
This is a high-impact opportunity for a clinically minded leader who enjoys driving late-stage strategy, navigating complexity, and helping bring meaningful therapies closer to patients.
Featured benefits
401(k), Medical insurance, Vision insurance, Dental insurance